HCFC1R1 Antibody, FITC conjugated

Datasheet

Code	CSB-PA865161LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HCFC1R1 Polyclonal antibody

Uniprot No.

Q9NWW0

Target Names

HCFC1R1

Alternative Names

HCF 1 beta propeller interacting protein antibody; HCF-1 beta-propeller-interacting protein antibody; HCF1 beta propeller interacting protein antibody; HCFC1R1 antibody; Host cell factor C1 regulator 1 (XPO1 dependent) antibody; Host cell factor C1 regulator 1 antibody; HPIP antibody; HPIP_HUMAN antibody; Inhibitor of four 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.

Gene References into Functions

HPIP overexpression is an independent predictor of platinum-based chemotherapy resistance in epithelial ovarian neoplasms. PMID: 27818289
HPIP promotes thyroid cancer cell growth, migration and epithelial mesenchymal transformation through activating PI3K/AKT signaling pathway. PMID: 26463629
HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion PMID: 25800793
HPIP regulates HCF-1 activity by modulating its subcellular localization PMID: 12235138

Subcellular Location

Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.

Tissue Specificity

Widely expressed.

Database Links

HGNC: 21198

KEGG: hsa:54985

UniGene: Hs.423103

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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